REGULATORY ROLES OF TRNA-DERIVED RNA FRAGMENTS IN HUMAN PATHOPHYSIOLOGY



Spatial genetic structure patterns of phenotype-limited and boundary-limited expanding populations: a simulation study.

Range expansions may create a unique spatial genetic pattern characterized by alternate genetically homogeneous domains and allele frequency clines.Previous attempts to model range expansions have mainly focused on the loss of genetic diversity during expansions.Using individual-based models, we examined spatial genetic patterns under two expansion

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Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: the Hisayama Study

Abstract Background Resistin, secreted from adipocytes, causes insulin resistance in mice.The relationship between resistin and coronary artery disease is highly controversial, and the information regarding resistin and ischemic stroke is limited.In the present study, the association between serum resistin concentration and cardiovascular disease (

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Factors influencing the determination of cell traction forces.

Methods summarized by the term Traction Force Microscopy are widely used to quantify cellular forces in mechanobiological studies.These methods are inverse, in the sense that forces must be determined such that they comply with a measured displacement field.This study investigates how several experimental and analytical factors, originating in the

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